Brain-Reactive Antibodies and Disease
نویسندگان
چکیده
منابع مشابه
Anticardiolipin Antibodies and Immunoglobulin M and A in Graves’ Disease
Background: Graves’ disease is an autoimmune disease, characterized by the presence of antibodies directed to TSH receptor or nearby regions as well as antibodies to double strands DNA (dsDNA) anticardiolipin and nuclear antibodies. This study evaluated anticardiolipin and rheumatoid factor, such as IgA and IgM antibodies in patients with Graves’ disease. Patients and methods: Anticardiolipin a...
متن کاملGanglioside reactive antibodies in the neuropathy associated with celiac disease.
We tested patients with celiac disease (CD) for the presence of serum anti-ganglioside antibodies. Six of twenty-seven patient sera were reactive against brain gangliosides by an agglutination immunoassay. Neurological examination in all six revealed the presence of distal sensory loss, consistent with the diagnosis of peripheral neuropathy. When tested by ELISA for antibodies to isolated GM1, ...
متن کاملHuman antibodies reactive with beta-amyloid protein in Alzheimer's disease
Four human B cell lines established by Epstein-Barr viral transformation of B cells from a patient with a clinical diagnosis of Alzheimer's disease (AD) were found to secrete antibodies that react with plaques and cerebrovascular blood vessels in AD brain in a staining profile characteristic of beta-amyloid protein (beta-AP) in AD brain. Two of these antibodies were shown to be reactive with a ...
متن کاملAntibodies and Brain Disease: A Convergence of Immunology and Physiology
I ncreasingly, patients with systemic lupus erythematosus (SLE) are recognized to have central nervous system (CNS) manifestations. Overt infl ammation in the CNS is rare, but impairment of cognition or mood disturbance is common. Treatment of infl ammation is directed at the underlying autoimmune disorder; treatment of other manifestations, including mood disorder, often focuses on symptom all...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annual Review of Immunology
سال: 2013
ISSN: 0732-0582,1545-3278
DOI: 10.1146/annurev-immunol-020711-075041